Modern biology may finally have begun to bring technological and scientific rigour to Fisher's decades-old insights.

hell yeah!

Scientists are spending tens of millions of dollars to find another genetic risk factor for diabetes. Hoorah!!!

Scientists are spending tens of millions of dollars to find another genetic risk factor for diabetes.

a SNP chip is around $250. this study was about 1500 people. add in costs to pay all the people that collect the samples, do the genotyping, etc., we're talking $500,000. cheap? no. worth it? I say yes.

I understand hyperbole, but do you have a point?

I understand hyperbole, but do you have a point?

they live and they breath. just like any dumb animal.

I think that $500,000 and tens of millions are both off by a factor of 10. Sample acquisition costs alone probably add at least several hundred dollars per sample to the cost.

Fair enough on the price tag, I must have missed that. Spending $500,000 to look for a potential risk factor in some people seems reasonable.

The money is worth it, but no direct clinical implications....

"Thus, although our findings can be the
source of valuable physiological insights, their contribution to the familial clustering and individual risk prediction of T2DM is relatively small."

Other chronic diseases might be the same (HTN, dyslipidemia, etc.) -- where genetic markers really don't help in risk prediction or patient stratification. That would be dissappointing.